计算机辅助硅胶假体建模、分析与制作方法
Computer-aided Modeling Analysis and Manufacturing Approach for Silicone Prosthesis
作者：王素(四川大学 制造科学与工程学院, 四川 成都 610065)；王鹏举(四川大学 制造科学与工程学院, 四川 成都 610065)；徐亮(四川大学 制造科学与工程学院, 四川 成都 610065)；杨洋洋(四川大学 制造科学与工程学院, 四川 成都 610065)；陈东华(四川大学 制造科学与工程学院, 四川 成都 610065)；吴晓南(四川大学 制造科学与工程学院, 四川 成都 610065)
Author：WANG Su(School of Manufacturing Sci. and Eng., Sichuan Univ., Chengdu 610065, China)；WANG Pengju(School of Manufacturing Sci. and Eng., Sichuan Univ., Chengdu 610065, China)；XU Liang(School of Manufacturing Sci. and Eng., Sichuan Univ., Chengdu 610065, China)；YANG Yangyang(School of Manufacturing Sci. and Eng., Sichuan Univ., Chengdu 610065, China)；CHENG Donghua(School of Manufacturing Sci. and Eng., Sichuan Univ., Chengdu 610065, China)；WU Xiaonan(School of Manufacturing Sci. and Eng., Sichuan Univ., Chengdu 610065, China)
收稿日期：2016-10-31 年卷（期）页码：2017,49(3):209-216
期刊名称：工程科学与技术
Journal Name：Advanced Engineering Sciences
关键字：硅胶假体;3维建模;有限元分析;3D打印;配比;模温;优化分析
Key words：silicone prosthesis;3D modeling;finite element method;3D printing;ratio;mold temperature;optimization analysis
基金项目：国家自然科学基金资助项目（61672363）；国家自然科学基金资助项目（61540006）；国家科技部重点专项资助项目（SQ2016YFSF100184）
中文摘要
为研究计算机辅助硅胶假体制作方法，以双组分硅橡胶为研究对象，参照人体用硅胶假体几何特征并根据普通小鼠乳房特性，综合考虑温度和材料属性参数，进行计算机辅助3维建模和模具、假体温度场数值模拟，分析假体表面实际受热温度与模具加热温度（以下简称模温）吻合情况；基于有限元分析方法，模拟假体模型受载状况，从柔软度和疲劳寿命2个方面探讨假体模型在修复胸壁软组织缺损中应用的可行性；基于打印材料和制作工艺，分析假体制备试验可行性，然后采用3D打印技术设计制备模具；综合考虑粘膜效应影响和交联反应效率，模温分别取5、25、60 ℃，进行硅胶假体制备实验。通过不同的硅胶与固化剂配比和模温处理，比较不同配比和模温对制备假体柔软度、黏度和脱模耗时的影响；基于最小二乘曲线拟合原理，数据优化分析，检验回归方程显著性，确定配比与模温。实验结果表明，一定范围内，配比对假体影响显著，模温对其影响甚微。当硅胶与固化剂配比为10∶0.43，模温为55 ℃时，所得假体具有良好柔韧性等特点。
英文摘要
Computer-aided manufacturing approach for silicone prosthesis with two-component silicone rubber was studied and modeled by 3D modeling.The model was based on temperature,material parameters and geometric features for body and normal mice.The temperature difference between mold and prosthesis surface was discussed by numerical simulation on the temperature field of die and prosthesis.The feasibility of the modeling in repairing the soft tissue defect of chest wall was validated by applying phantom load from softness and fatigue life.The verification was based on finite element method.The test feasibility was based on printing material and manufacturing process.The mold were manufacturing by 3D printing.The test were carried out based on the effects of mucosal and crosslinking reaction efficiency in die at 5,25 and 60 ℃.The effects of prosthesis softness,viscosity and stripping time were discussed by choosing different ratio of silicone and curing agent and temperature.The ratio and temperature were determined by optimizing data in the least square method and examing the regression equation prominence.The results showed that the prosthesis is affected by ratio,but not by temperature within certain range.The soft prostheses are generated when the ratio is set in 10∶0.43,and at 55 ℃.
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