Large-diameter steel pipe pile is a kind of single pile which is widely used in offshore wide farm. Based on the centrifugal model test results of large-diameter steel pipe pile under horizontal load, we conducted the centrifugal numerical test by 3D finite element method. Elastic modulus has the important influence on the deformation of the steel pipe pile under horizontal load. Through optimizing the elastic modulus, it is verified that the distributions of the deformation of pile top, the deflection and the bending moment of pile shaft by numerical method is consistent with those in model test. Then, we obtained the load-displacement relationship of steel pipe pile at different depths under horizontal load, and got the systematic knowledge for the horizontal resistance of foundation in different soil layers. So, the numerical test can overcome the deficiency that the monitoring data is limited and the arrangement of monitoring instrument is difficult in model test. Moreover, the load-displacement relationship by numerical method has common applicability, and the numerical test results can be references for actual projects.