How to concretely measure and explicitly reduce the interference of the entire network becomes a major challenge. A new protocol interference model is presented as a measure to describe the interference of the entire network in this paper. Furthermore we propose a distributed interference-avoidance topology control approximation algorithm, referred to as the ISPT. The algorithm minimizes the interference in the network according to our metrics while preserving the connectivity of the resulting topology. The simulation results show that ISPT decreases interference and improves network capacity in terms of throughput.