The Tanning Matrix can be formed by resorcinol and oxazolidine E, and the reaction properties between Tanning Matrix and collagen has been investigated through NMR and size distribution analysis. The collagen was simulated with glycin. The results have showed that the molar combination ratio of Matrix as congeries between oxazolidine E and resorcinol was 2:1 or 3:2, the reaction positions were C(5) and C(6) of oxazolidine E and C(4) or C(6) of resorcinol. And the hydroxymethyl of oxazolidine E and amino group of collagen bonded with covalent bond, phenol hydroxyl group of resorcinol and amino group of collagen combined with hydrogen bond.
