In order to investigate the treatment efficiency of intetrated MBR for chemical industry wastewater treatment, an 80m3/d full-scale internal circulation integrated MBR with particle carriers was used to treat chemical industry wastewater for about one hundred days. The results showed that when the influent concentration of CODCr, NH3-N and TP were 153.20~594.68mg•L-1, 2.02~23.79mg•L-1 and 3.36~13mg•L-1, respectively. The water quanlity of effluent was stable after 90 days’ operation performance.And the effluent concentration of CODCr, NH3-N and TP were lower than 50mg•L-1,3mg•L-1 and 1mg•L-1, the removal were 80.25%~87.15%, 73.32%~99.78% and 87.09%~93.82%. The color and pH value of effluent were 25~40 times and 6.79~7.83. And the effluent was clear and without stimulated smell. The treatment efficiency of membrane bioreactor was improved by adding particle carriers, which continuously scoured and collidded membrane surface, resulting in alleviating membrane fouling.