For optimizing the Grid resource management and task scheduling effectively, a Grid Resource's Domain Split Management Method (GR-DSMM) was presented, which was based on association rules to group the sub-tasks. Firstly, in order to enhance the association between the sub-tasks in one sub-task-group and strengthen the independency between the groups, the method grouped all sub tasks, which was syncopated in users' tasks according to the association between the sub-tasks. Next, the GR-DSMM took the sub-task-group as one execution unit, which could reduce the frequent communication between the sub-task-groups, and could improve the system's efficiency. At the same time, the method divided the grid resources into domain split according to the sub-task group's resource demands. The method managed the Grid resources taking a domain split as one basic unit. Finally, the performance of GR DSMM was compared with that of multiple queue Backfilling scheduling algorithm and FCFS scheduling policy by emluator, and the superiority and practicability of this method was proved.