In this paper, we investigate the weak solution of the following porous medium equation with fractional diffusion: 〖JB({〗〖HL(1:1,Z〗〖SX(〗u〖〗t〖SX)〗+(-Δ)σ/2um=F(u),x∈ R N,t>0,u〖JB((〗x,0〖JB))〗=f(x),x∈ R Ν.〖HL)〗〖JB)〗 Forf∈L1( R N)∩L∞( R N),m>0 and 0