The dental follicle originated from the ectomesenchyme is the genetic tissue of cementum, alveolar bone and periodontal ligament. It is believed that this tissue is not homogeneous cell populations, but contains stem cells and lineage committed progenitor cells or precursor cells for cementoblasts, periodontal ligament cells, and osteoblasts, so dental follicle cells have heterogeneity. The research of dental follicle cell heterogeneity was reviewed in this paper.
