Oral cancer is a one of the most important killer which threaten human’s healthy severely. People usually have little acquaintance with it and treat it not seriously enough at the early stage; Additionally, the stimulations from the movement of the tongue and oral cavity when people are masticating and talking also can promote cancer cells metastasis. Consequently, the prognosis of oral cancer is usually pessimistic. In the recent years, some research validated that some molecules correlate with the tumorigenesis and progression of oral cancer, which provide probability for the early diagnosis and therapy for the oral cancer. Therefore, this review will discuss the detection of saliva and the selection of the biomarkers of the oral cancer.
