Objective To assess the efficacy of microwaves treatment, pingyangmycin injection and resection treatment for mucocele. Methods 123 participants who were diagnosed as mucocele of the salivary gland were included and allocated to microwaves group（n=35）, pingyangmycin group（n=40） and resection group（n=48） and were treated accordingly. The follow-up period was 6 months. Results All the participants were followed-up. The baseline variables differed a little. The cure rate of microwaves was 94.29%, pingyangmycin 95.00% and resection 95.83%. There was no statistical significance between three therapeutic strategies（P＞0.05）. Conclusion Microwaves treatment and pingyangmycin injection is reliable supplementary to resection treatment and could be considered for the pediatric patients or patients who could not recover from the surgery or do not want surgery.
