Bone substitute materials are widely used in the process of repairing bone defect, the addition of factors promoting bone regeneration is the main hot spots in the research of bone substitute materials. As a necessary trace element, strontium can simultaneously stimulate new bone formation and reduce bone absorptionin vivo. In recent years, many scholars combined strontium with all kinds of bone substitute materials, found that strontium can not only improve the physical and chemical properties of bone substitute materials, but also can change cell behavior, improve the abilities of osteogenesis. This article summarized the above aspects of strontium-doping bone substitute materials.
