基质小泡及其与细胞骨架蛋白的关系
Matrix vesicles and their relationship with cytoskeleton-associated proteins
作者：冼雪红, 蒋宏伟
Author：Xian Xuehong, Jiang Hongwei
收稿日期：2017-04-28 年卷（期）页码：2018,45(2):204-208
期刊名称：国际口腔医学杂志
Journal Name：International Journal of Stomatology
关键字：基质小泡,蛋白质组学,矿化相关蛋白质,骨架相关蛋白质,
Key words：matrix vesicles,proteomic analysis,mineralization-related protein,cytoskeleton-associated protein,
基金项目：广东省自然科学基金（2014A030313166,2017A030313713）
中文摘要
基质小泡作为与矿化密切相关的囊泡,在分泌和矿化过程中实现的多种功能与自身富含的相关蛋白质密不可分。本文就基质小泡及其提取和纯化、蛋白质组学,以及参与其分泌的细胞骨架蛋白等的研究进展进行综述,以便深入认识其相关蛋白质的作用机制,为临床促进矿化研究提供理论依据。
英文摘要
Matrix vesicles are small vesicles closely associated with mineralisation. During the formation and mineralisation of matrix vesicles, most functions are closely related to their own proteins. This article aims to review the research progress on matrix vesicles, their extraction and purification and proteomic and cytoskeleton-associated proteins related to secretion. Understanding the functions of related proteins and the underlying mechanisms contributes in providing theoretical basis for clinical research on mineralisation.
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