宣威乌头中生物碱成分的研究
Study on the diterpenoid alkaloids from Aconitum nagarumvar lasiandrum
作者:蒋莹莹;陈东林;
Author:
收稿日期: 年卷(期)页码:2017,32(02):-117-120
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:乌头属;宣威乌头;C_(20)-二萜生物碱;C_(19)-二萜生物碱
Key words:
基金项目:国家自然科学基金资助项目(批准号:81072550)
中文摘要
目的研究宣威乌头Aconitum nagarumvar lasiandrum中的生物碱成分。方法采用酸提碱沉法提取总碱、硅胶层析法分离,用波谱法鉴定结构。结果和结论从宣威乌头中分得10个单体化合物,应用光谱法鉴定了其结构为:光翠雀碱(denudatine)、宋果灵(songorine)、delnuttaline等3个C_(20)-二萜生物碱和尼奥灵(neoline)、3-去氧乌头碱(3-deoxyaconitine)、8-methoxy-14-benzoylaconine、伏乌碱(flavaconitine)、异塔拉萨敏(isotalatizidine)、乌头碱(aconitine)和nevadensine等7个C_(19)-二萜生物碱。
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