龙血竭总酚滴丸对大鼠局灶性脑缺血损伤的保护作用
Protective effect of Dragon's blood total phenolic dropping- pill on focal cerebral ischemia in the rats
作者:郑焱江;梁楠;廖诗平;植茂辉;杨芳炬;
Author:
收稿日期: 年卷(期)页码:2014,29(01):-45-47
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:龙血竭总酚滴丸;局灶性脑缺血;神经功能评分;梗塞体积
Key words:
基金项目:
中文摘要
目的观察龙血竭总酚滴丸对大鼠局灶性脑缺血的保护作用。方法采取线栓法制造大鼠右侧大脑中动脉栓塞模型。将大鼠分为假手术组、模型组、对照组、龙血竭原料药组及龙血竭总酚滴丸高、中、低剂量组,各给药组ig给药,qd,连续4 d,第5天上午继续给药1次,1 h后进行手术,术后24 h时,对各组大鼠分别进行神经功能评分,处死并测定梗死体积。结果龙血竭总酚滴丸各剂量组均可显著降低大鼠脑缺血后神经功能的评分(P
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