新型查尔酮类化合物TPY的抗氧化及抗菌活性研究
Studies on antioxidant and antimicrobial activities of a novel chalcone compound TPY
作者:裘观荣;丁晓丽;黄巧珍;关丽萍;
Author:
收稿日期: 年卷(期)页码:2013,28(04):-343-345
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:查尔酮类;化合物TPY;抗氧化活性;抑菌活性
Key words:
基金项目:浙江省自然科学基金项目(项目编号:LY12C19005)
中文摘要
目的研究查尔酮类化合物TPY的抗氧化、抗菌活性。方法测定TPY对DPPH.清除能力和总还原能力,测定TPY对大肠杆菌、金黄色葡萄球菌、枯草芽孢杆菌、沙门氏菌和变形杆菌等菌种的体外抑菌作用。结果 TPY的抗氧化能力呈现出明显的剂量依赖关系,具有良好的抗氧化活性。TPY对5种病菌具有不同程度的抑制作用。结论 TPY可作为一种理想的抗氧化和抑菌添加剂。
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