不同采收期栀子药材中有效成分的含量与清除自由基活性的相关性研究
Investigation of the relationship between investigation of crocins and geniposide contents and radical scavenging activity of Gardenia at the various stages of maturation
作者:陈阳;张浩;蔡乐;王雅溶;蔡仕宁;
Author:
收稿日期: 年卷(期)页码:2014,29(04):-405-406
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:栀子;西红花苷;栀子苷;DPPH自由基;高效液相色谱法;相关性
Key words:
基金项目:国家自然科学基金资助项目(批准号:21162046)
中文摘要
目的研究不同生长期栀子药材中西红花苷和栀子苷的含量与药材清除自由基活性的相关性。方法以前期分离的西红花苷和栀子苷为对照品,采用HPLC测定不同采收期栀子药材中两化合物的含量,并测定药材DPPH自由基的清除活性。结果 HPLC方法准确度和精密度高,方法稳定,线性关系好,西红花总苷含量从8月中旬的0.009%增加到11月中旬的1.32%,而栀子苷则从8月中旬的6.01%降低到12月中旬的2.86%;药材清除自由基的活性变化较小。结论栀子中西红花苷和栀子苷的含量和清除DPPH自由基的能力无相关性。
参考文献
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