赛红霉素的合成工艺
Synthesis process of Cethromycin
作者：周忠华;刘楠;邓昱星;李盛男;马文博;何菱;
Author：
收稿日期： 年卷（期）页码：2011,26(01):-20-23
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：大环内酯类抗生素;酮内酯;赛红霉素;合成
Key words：
基金项目：
中文摘要
目的改进赛红霉素的合成工艺。方法以红霉素A为原料,经肟化、酯化、烃基化、脱保护、脱肟、环氨甲酸酯化、酸水解、氧化和去保护等10步反应合成目标化合物。结果和结论改进后的方法操作简便,成本降低。
参考文献
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