多靶点趋化因子功能抑制剂的研究进展
作者:刘毅;孙晗笑;
Author:
收稿日期: 年卷(期)页码:2010,25(02):-232-235
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:趋化因子;多靶点;抑制;炎症
Key words:
基金项目:国家自然科学基金资助项目(批准号:30872221)
中文摘要
趋化因子系统作为各种急慢性炎症疾病新的治疗靶点,由于自身的冗余性,使得传统的以单一趋化因子或其受体为靶标的特异性拮抗剂的效果甚微,开发具有多靶点抑制趋化因子功能的药物已成为必然。
参考文献
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