西替利嗪和特非拉丁对皮试风团抑制指数的影响
EFFECT OF CETIRIZINE AND TEFENADINE ON SKIN TEST INHIBIT INDEX
作者:张谊之,张敏,黄正华
Author:
收稿日期: 年卷(期)页码:2001,(03):-169-170
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:风团;风团抑制指数;西替利嗪
Key words:
基金项目:
中文摘要
目的:了解西替利嗪对荨麻疹风团抑制的作用。方法:采用随机设计,以西替利嗪治疗为实验组,以特非拉丁治疗为对照组,对60例慢性尊麻疹患者,进行尘螨皮试诱发风团抑制情况的对比研究。结果:服药前两组间的风团面积无显著性差异。服用2周时,西替利嗪组对风团的抑制明显优于特非拉丁组,差异具显著性(P<0.05)。通过进一步的剂量一反应关系研究,曲线拟合所确定的风团抑制指数表明,前者的抑制作用是后者的9倍。结论:西替利嗪对风团抑制的作用优于特非拉丁。
参考文献
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