抗HIV活性香豆素类化合物的研究进展
PROGRESS IN STUDIES OF ANTI-HIV COUMARINS
作者：杨劲松
Author：
收稿日期： 年卷（期）页码：2001,(04):-285-288
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：爱滋病;抗HIV;香豆素类化合物;综述
Key words：
基金项目：
中文摘要
目的 :综述近年来抗HIV活性香豆素类化合物的研究进展。方法 :以实例说明。结果 :以天然抗HIV活性香豆素类化合物为先导物 ,筛选到许多显著抑制HIV的衍生物。结论 :为研制抗爱滋病药物提供了一个新的途径
参考文献
1 LaurenceJ.AIDSresearch:theseconddecade[J].AIDSResHumRetrov,1994,10:1585
2 马培奇.爱滋病治疗药物最近进展[J].中国医药情报,1997,3(3):182
3 St.ClairMH ,MartinJL ,TudorWilliamsG ,etal.ResistancetoddIandsensitivitytoAZTinducedbyamutationinHIV 1reversetranscrip tase[J].Science,1991,253:1557
4 乐长高,黄国林.抗HIV活性天然产物[J].天然产物研究与开发,1999,11:90
5 BourinbaiarAS ,TanX ,NagoruyR ,etal.Effectoftheoralanticoagu lant,warfarin,onHIV 1replicationandspread[J].AIDS ,1993,7:129
6 TumminoPJ ,FergusonD ,HupeD ,etal.CompetitiveinhibitionofHIV 1proteasebywarfarinderivatives[J].BiochemBiophysResCom mun,1994,201:290
7 TumminoPJ ,FergusonD ,HupeD ,etal.CompetitiveinhibitionofHIV 1proteaseby4 hydroxybenzopyran2 onesandby4 hydroxy6 phenylpyran2 ones[J].BiochemBiophysResCommun,1994,200:1658
8 RominesKR ,ChruscielRA .4HydroxypyronesandrelatedtemplatesasnonpeptidicHIVproteaseinhibitors[J].CurrMedChem,1995,2:825
9 SkulnickHI,JohnsonPD ,AristoffPA ,etal.Structure baseddesignofnonpeptidicHIVproteaseinhibitors:thesulfonamide substitutedcy clooctylpyranones[J].JMedChem,1997,40:1149
10 LeeTTY ,KashiwadaY ,HuangL ,etal.AntiAIDSagents13.Suks dorfin:anantiHIVprinciplefromLomatiumsuksdorfii,itsstructureactivitycorrelationwithrelatedcoumarins,andsynergisticeffectswithantiAIDSnucleoside[J].BioorgMedChem,1994,2:1051
11 LeeKH ,MorrisNatschkeSL .Recentadvancesinthediscoveryandde velopmentofplant derivednaturalproductsandtheiranalogsasantiHIVagents[J].PureApplChem,1999,71:1045
12 HuangL ,KashiwadaY ,CosentinoM ,etal.AntiAIDSagents15.SynthesisandantiHIVactivityofdihydroseselinsandrelatedanalogs[J].BioorgMedChemLett,1994,4:593
13 XieL ,TakeuchiY ,CosentinoM ,etal.AntiAIDSagents33.Synthe sisandantiHIVactivityofnon methylsubstituted3′,4′ diO (-) camphanoyl(+) cis khellactone(DCK )analogs[J].BioorgMedChemLett,1998,8:2151
14 TakeuchiY ,XieL ,CosentinoM ,etal.AntiAIDSagents28.Synthe sisandantiHIVactivityofmethoxysubstituted3′,4′ diO (-) cam phanoyl(+) cis khellactoneanalogs[J].BioorgMedChemLett,1997,7:2573
15 YangZY ,XiaY ,XiaP ,etal.AntiAIDSagents31.SynthesisandantiHIVactivityof4 substituted3′,4′ diO (-) camphanoyl(+) cis khellactone(DCK)thiolactoneanalogs[J].BioorgMedChemLett,1998,8:1483
16 KashmanY ,GustafsonKR ,FullerRW ,etal.Thecalanolides,anov elHIV inhibitoryclassofcoumarinderivativesfromthetropicalrainfor esttree,Calophyllumlanigerum[J].JMedChem,1992,35:2735
17 TaylorPB ,CulpJS ,DebouckC ,etal.Kineticandmutationalanalysisofhumanimmunodeficiencyvirustype1reversetranscriptaseinhibitionbyinophyllums,anovelclassofnon nucleosideinhibitors[J].JBiolChem,1994,269:6325
18 BuckheitRW ,FliakasBoltzV ,DeckerWD ,etal.ComparativeantiHIVevaluationofdiverseHIV 1 specificreversetranscriptaseinhibitor resistantvirusisolatesdemonstratestheexistenceofdistinctphenotypicsubgroups[J].AntiviralRes,1995,26:117
19 PatilAD ,FreyerAJ,EgglestonDS ,etal.Theinophyllums,novelin hibitorsofHIV 1reversetranscriptaseisolatedfromtheMalaysiantree,CalophylluminophyllumLinn[J].JMedChem,1993,36:4131
20 FlavinMT ,RizzoJD ,KhilevichA ,etal.Synthesis,chromatographicresolution,andanti humanimmunodeficiencyvirusactivityof(±) calanolideAanditsenantiomers[J].JMedChem,1996,39:1303
21 PengsuparpT ,SeritM ,HughesSH ,etal.Specificinhibitionofhumanimmunodeficiencyvirustype1reversetranscriptasemediatedbysoulat trolide,acoumarinisolatedfromthelatexofCalophyllumteysmannii[J].JNatProd,1996,59:839
22 CardellinaJH ,BokeschHR ,McKeeTC ,etal.Resolutionandcom parativeantiHIVevaluationoftheenantiomersofcalanolidesAandB[J].BioorgMedChemLett,1995,5:1011
23 DharmaratneHRW ,SotheeswaranS ,BalasubramaniamS ,etal.Triter penoidsandcoumarinsfromtheleavesofCalophyllumcordato oblongum[J].Phytochemistry,1985,24:1553
24 CheneraB ,WestML ,FinkelsteinJA ,etal.Totalsynthesisof(±) calanolideA ,anon nucleosideinhibitorofHIV 1reversetranscriptase[J].JOrgChem,1993,58:5605
25 KucherenkoA ,FlavinMT ,BoulangerWA ,etal.Novelapproachforsynthesisof(±) calanolideAanditsantiHIVactivity[J].Tetrahe dronLett,1995,36:5475
26 PalmerCJ ,JosephsJL .SynthesisoftheCalophyllumcoumarins.Part2[J].JChemSocPerkinTransl,1995,3135
27 周春梅,王琳,张铭龙,等.抗人免疫缺陷病毒(HIV)天然产物CalanolideA及其类似物的合成[J].药学学报,1999,34:673
28 DeshpandePP ,TagliaferriF ,VictorySF ,etal.SynthesisofopticallyactivecalanolidesAandB[J].JOrgChem,1995,60:2964
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