新型高密度氨基肽类树枝状化合物G_1的合成及表征
Synthesis and characterization of new first generation dendrimers with high-density amine groups
作者：江德洪;郑虎;齐庆蓉;
Author：
收稿日期： 年卷（期）页码：2010,25(06):-647-649
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：高密度氨基肽类树枝状化合物;L-2,3-二氨基丙酸;丙二酸二乙酯
Key words：
基金项目：
中文摘要
目的合成以L-2,3-二氨基丙酸为支化基元的新型高密度氨基肽类树枝状化合物G1。方法以丙二酸二乙酯为起始原料,经缩合、氢化还原,再胺解得到母核。将支化基元L-2,3-二氨基丙酸通过活性酯与母核以酰胺键相连接。结果和结论合成了2个未见文献报道的新型高密度氨基肽类树枝状化合物,并经1HNMR、13CNMR、MS确证化学结构。
参考文献
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