苦马豆素对肝癌细胞在体内外生长的抑制作用
Inhibition on the growth of Swainsonine to hepatocarcinoma in vivo and in vitro
作者：孙纪元;朱妙章;王四旺;谢艳华;王剑波;缪珊;
Author：
收稿日期： 年卷（期）页码：2006,(03):-221-224
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：苦马豆素;肝癌;HHCC细胞;H22瘤细胞;MTT实验
Key words：
基金项目：
中文摘要
目的研究苦马豆素(Sw)对肝癌细胞在体内外生长的抑制作用。方法采用体外抑瘤试验培养人源性肝癌HHCC细胞的方法,通过MTT法等试验测定其体外抑癌浓度;体内试验采用小鼠的鼠源性肝癌H22移植瘤法,通过对抑瘤率及病理切片的观测,探讨其抑瘤作用。结果3.84μg.ml-1的Sw体外作用72 h后,HHCC细胞的存活率明显下降(P
参考文献
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