CEF与TE剂量密集方案治疗原发性乳腺癌的新辅助化学疗法
作者:赵丽娟;汪静;贺平;刘雪娟;
Author:
收稿日期: 年卷(期)页码:2007,(04):-459-461
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:乳腺癌;新辅助化疗;表阿霉素;紫杉醇;剂量密集
Key words:
基金项目:
中文摘要
目的观察CEF(环磷酰胺+表阿霉素+氟尿嘧啶)与TE(紫杉醇+表阿霉素)剂量密集方案治疗原发性乳腺癌新辅助化疗的临床疗效和不良反应。方法应用CEF与TE双周剂量密集化疗方案对62例女性Ⅱa~Ⅲc期原发性乳腺癌患者进行新辅助化疗。结果CEF组临床有效率为61.3%,病理完全缓解率为6.5%,疾病进展为3.2%;TE组分别为87.1%、9.7%。Ⅱb~Ⅲc期的局部进展期乳腺癌,CEF组RR为60.7%,TE组为85.2%,两组间临床疗效有显著性差异(P
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