抗肿瘤药物脂质体粒径对肿瘤靶向性的影响
作者：杨莉斌;沈静;胡荣;
Author：
收稿日期： 年卷（期）页码：2007,(04):-428-430
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：脂质体;粒径;肿瘤;积聚;血液循环;药物释放
Key words：
基金项目：
中文摘要
根据脂质体在血液中的分布和储留时间、在肿瘤组织中的积聚、从肿瘤毛细血管中渗漏及其在肿瘤组织中截留的研究,综述了脂质体的粒径在药物动力学中发挥的作用,并讨论了其粒径在设计抗肿瘤脂质体药物时的重要性。
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