角质海绵和沙海绵中二倍半萜的结构与抗肿瘤活性的关系
作者:刘永宏;季红;张偲;李立冬;费丽娜;
Author:
收稿日期: 年卷(期)页码:2007,(04):-426-428
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:角质海绵;沙海绵;二倍半萜;抗肿瘤活性;构效关系
Key words:
基金项目:中国科学院重要方向项目(KZCX2-YW-216);;
中国科学院王宽诚科研奖金项目(20050904092746)
中文摘要
综述角质海绵和沙海绵中线型二倍半萜类成分的结构和生物活性。结合体外抗肿瘤活性测试结果,探讨该类化合物的结构与抗肿瘤活性的关系。
参考文献
[1]邓松之.海绵的生理活性物质[J].中国海洋药物,1988,7(1):44-48.
[2]肖定军,邓松之.海绵生理活性物质研究新进展[J].广州化学,1996,1:57-67.
[3]Shin J,Rho JR,Seo Y,et al.Sarcotragins Aand B,newsester-terpenoid alkaloids from the spongeSarcotragus sp.[J].Tetra-hedron Lett,2001,42:3005-3007.
[4]Perry NB,Battershill CN,Blunt JW,et al.Occurrence of vari-abilin in New Zealand sponges of the order Dictyoceratida[J].Biochem Syst Ecol,1987,15:373-376.
[5]Murray L,Hamit H,Hooper JNA,et al.Anewsesterterpene te-tronic acid from an Australian marine spongePsammocinia sp.[J].Aust J Chem,1995,48:1899-1902.
[6]Liu Y,Hong JK,Lee CO,et al.Cytotoxic pyrrolo-andfuranoterpenoids from the spongeSarcotragus species[J].J NatProd,2002,65:1307-1314.
[7]Murray L,Sim ATR,Rostas JAP,et al.Isopalinurin:a mildprotein phosphatase inhibitor from a southern Australian marinesponge Dysidea sp.[J].Aust J Chem,1993,46:1291-1294.
[8]Choi K,Hong JK,Lee CO,et al.Cytotoxic furanosesterterpenesfrom a marine spongePsammocinia sp.[J].J Nat Prod,2004,67:1186-1189.
[9]Liu Y,Mansoor TA,Hong JK,et al.New cytotoxic sesterterpe-noids and norsesterterpenoids from two sponges of the genusSar-cotragus[J].J Nat Prod,2003,66:1451-1456.
[10]Liu Y,Bae BH,Alam NJ,et al.New cytotoxic sesterterpenesfrom the spongeSarcotragus species[J].J Nat Prod,2001,64:1301-1304.
【关闭】