7-[(2-羟基-3-哌啶)-丙氧基]-异黄酮的合成及抗肿瘤活性
Synthesis of 7-[(2-hydroxyl-3-piperidino)-propoxy]-isoflavone and anti-cancer activity
作者：戴德明;翁玲玲;
Author：
收稿日期： 年卷（期）页码：2007,(06):-626-629
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：异黄酮;环氧氯丙烷;合成;肿瘤
Key words：
基金项目：国家科技部973计划项目(2004CB518800)
中文摘要
目的合成7-[(2-羟基-3-哌啶)-丙氧基]-异黄酮衍生物。方法以2-位取代的异黄酮与环氧氯丙烷反应,再与哌啶反应,得目标化合物。结果与结论合成了5个目标化合物,经结构确证、药理活性测定,均具有一定的抗肿瘤活性。
参考文献
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