RGD序列肽偶联物的研究进展
作者:杨大成,肖晴,钟裕国
Author:
收稿日期: 年卷(期)页码:2003,(01):-45-47
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:RGD序列肽;偶联物;合成;生物活性
Key words:
基金项目:
中文摘要
目的 综述并介绍RGD序列肽与多酸、抗癌药、CM -Chitin、PEG、PEU、EAA、CEMA等偶联物的合成方法。其合成一般采用缩合剂将肽和其他组分连接起来 ,偶联物的生物活性较其非偶联物强 ,是很有前途的多肽类药物 ,值得继续研究。
参考文献
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