地塞米松抑制肿瘤坏死因子α介导的肾小球系膜细胞
DXM inhibited glomerular mesangial cells mediated by TNFα
作者:杨立川,屈燧林,马行一,刘先蓉
Author:
收稿日期: 年卷(期)页码:2003,(01):-25-27
期刊名称:华西药学杂志
Journal Name:WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字:肿瘤坏死因子α;系膜细胞;地塞米松
Key words:
基金项目:
中文摘要
目的 探讨肿瘤坏死因子α(TNFα)对人肾小球系膜细胞 (MC)促增殖效应及地塞米松 (DXM)对其的抑制作用。方法 培养人肾MC ,采用3 H -胸腺嘧啶掺入法 (3 H -TdR掺入法 )测定MC增殖 :ELISA法测定细胞因子 (IL1)及细胞外基质ECM(FN、LN)。结果 TNFα明显刺激MC3 H -TdR掺入 ,与对照组比较P
参考文献
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