高效液相色谱法测定替尼泊甙注射液含量
DETERMINATION OF TENIPOSIDE INJECTION BY HPLC
作者：吴苏澄,姜云平,钟义,邵文军
Author：
收稿日期： 年卷（期）页码：1997,(02):-117-118
期刊名称：华西药学杂志
Journal Name：WEST CHINA JOURNAL OF PHARMACEUTICAL SCIENCES
关键字：高效液相色谱法;替尼泊甙;含量测定
Key words：
基金项目：
中文摘要
采用高效液相色谱法测定替尼泊甙注射液含量，替尼泊在0．05～5μl／10μl浓度范围内线性良好，r=0．9999。方法回收率为100．82，RSD＜0．95％。方法简便、准确、灵敏。
参考文献
1Peter I,Maurice LS.The clinical pharmacology of etoposide and teniposide.Clinical Pharmacokinetics,1987,12:223
2Canal P,Micbel C,Bugat R,et al.Quantification of tenipo side in human serum by HPLC with electrochemlcal detec tion.J Chromatogr,1986,375(2): 451
3Sinkule JA,Evans WE.HPLC andysis of semisynthet ic epipodophyllotoxins teniposide and etoposide using eletrochemical detection.J Pharm Sci,1984,73(2):164
4Holthuis JJM,Van Oort WS.Pinedo HM.A sensitive HPLC method for determination of the antineoplastic agents VP16-213 and VM26 in biological fluids. Anal Chim Acta, 1991,130(1) : 23
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