Objective This study aims to summarize the nursing experience in the internal sinus floor elevation surgery with piezosurgery. Methods The medical records of 48 patients who underwent sinus floor elevation surgery with piezosur-gery in the Department of Implantation, West China Hospital of Stomatology, Sichuan University, were reviewed. The pre-operative, intraoperative, and postoperative nursing methods were summarized. Results All 48 patients underwent smooth surgeries and did not encounter complications. Conclusion Careful preoperative preparation, careful and meticulous intra-operative nursing cooperation, and provision of sufficient health education after surgery to the patients are the key factors that ensure the success of internal sinus floor elevation surgery with piezosurgery.