Objective To research the relationship between the virulence factors of Saccharomyces albicans（S.albicans） and the random amplified polymorphic DNA（RAPD） bands of them, and establish the regression model by multiple regression analysis. Methods Extracellular phospholipase, secreted proteinase, ability to generate germ tubes and adhere to oral mucosal cells of 92 strains of S.albicans were measured in vitro; RAPD-polymerase chain reaction（RAPDPCR） was used to get their bands. Multiple regression for virulence factors of S.albicans and RAPD-PCR bands was established. Results The extracellular phospholipase activity was associated with 4 RAPD bands: 350, 450, 650 and 1 300 bp（P
