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论文摘要

肥大细胞、Clusterin/apoJ和转化生长因子-β在不同时期血管瘤中的表达及相关性

Expression and correlation of mast cell, Clusterin/apoJ and transforming growth factor-β in the different stages of human dermal hemangioma

作者:袁尉力 秦兴军 王绪凯

Author:YUAN Wei-li1, QIN Xing-jun2, WANG Xu-kai2

收稿日期:2009-08-25          年卷(期)页码:2009,27(04):361-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:血管瘤,血管内皮细胞,肥大细胞,Clusterin/apoJ,转化生长因子-β,

Key words:hemangioma,vascular endothelial cells,mast cell,Clusterin/apoJ,transforming growth factor-β,

基金项目:

中文摘要

目的探讨肥大细胞、Clusterin/apoJ和转化生长因子-β(TGF-β)在不同时期血管瘤发生、发展过程中的表达及相关性。方法采用免疫组织化学方法检测不同时期血管瘤中Clusterin/apoJ、TGF-β的表达水平以及采用甲苯胺蓝染色法对各期肥大细胞进行染色。结果增生晚期肥大细胞计数明显多于增生早、中期(P

英文摘要

Objective To investigate the expression and correlation of mast cell, Clusterin/apoJ and transforming growth factor-β(TGF-β) in the different stages of human dermal hemangioma. Methods Immunohistochemical stain technique(SABC) and toluidine blue(TB) stain technique were respectively used to detect the expression level of Clusterin/apoJ and TGF-β and the number of mast cells in the different stages of human dermal hemangioma. Results There was remarkable statistical difference between the advanced stage of proliferative hemangioma and the other stages of proliferative hemangioma in the number of mast cell(P

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