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论文摘要

植物乳杆菌HO-69的口腔益生性质研究

Probiotic characteristics of Lactobacillus plantarum HO-69 applied in oral cavity

作者:杨颖 陈卫 张灏汤坚

Author:YANG Ying1,2, CHEN Wei1, ZHANG Hao1, TANG Jian1

收稿日期:2008-10-25          年卷(期)页码:2008,26(05):482-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:植物乳杆菌,口腔,黏附,抑菌谱,

Key words:Lactobacillusplantarum,oralcavity,adhesion,inhibitoryspectrum,

基金项目:

中文摘要

目的研究植物乳杆菌HO-69在口腔中的益生性质。方法在体外模拟口腔硬组织,研究菌株对牙面与牙本质的黏附率;以MATH法确定其表面疏水性与电荷,推测菌株对口腔软组织的黏附率;以杯碟法研究其抑菌活性。结果植物乳杆菌HO-69菌株对于模拟牙面与牙本质的黏附率非常低,具有较高的表面疏水性、酸碱电荷与良好抑菌活性。结论植物乳杆菌HO-69引发龋病与促进龋病发展的概率很低,具有广谱的抑菌活性,是潜在的口腔益生菌。

英文摘要

Objective To investigate the probiotic characteristics of Lactobacillus plantarum(L.plantarum) HO-69 in oral cavity. Methods The adhesion ratios to teeth and dentine surface were determined by in vitro models. Hydrophobicity and surface charges were measured by MATH method. Inhibitory activity was measured by agar well diffusion method. Results The adhesion ratios to hard tissue were quite low. The hydrophobicity and surface charges were high, and it exhibited inhibitory activity against some pathogens. Conclusion The probability is low for L. plantarum HO-69 to initiate or accelerate dental caries. It shows broad-spectrum inhibitory activity and is potential probiotics applied in oral cavity.

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