Objective To explore the manufacture and clinical application of IPS - Empress casting ceramic restorations. Methods The problems in manufacture and clinical operation of 215 casting ceramic restorations were analyzed. Results In 215 casting ceramic restorations, 12(5.58%) casting ceramic restorations were affected by clinical design or application, 15(6.98%) casting ceramic restorations were affected by some manufacture problems, and 14(6.51%) casting ceramic restorations were affected by clinical try- in. Through 2 - 3 years′follow- up, the achievement ratio of 215 IPS- Empress casting ceramic restorations was 94.88%, and 11 casting ceramic restorations were affected by some problems. Conclusion Beauty and simultaneous enamel wear are the characteristics of casting ceramic restorations. But because of its brittle, the indications should be strictly selected.