纳米复合材料nHA-PA66对感染根管细菌的体外抑菌作用
Antibacterial Effect of nHA-PA66in vitro
作者：叶玲;苏勤;周学东;肖晓蓉
Author：YELing1,SUQin1,ZHOUXue-dong1,XIAOXiao-rong2
收稿日期：2005-12-25 年卷（期）页码：2005,23(06):522-
期刊名称：华西口腔医学杂志
Journal Name：West China Journal of Stomatology
关键字：抗菌性,nHA-PA66,优势菌,感染根管,
Key words：antibacterial activity,nHA-PA66,predominant bacterial,infected root canal,
基金项目：四川省科委科技攻关资助项目(02SG022-001)
中文摘要
目的 研究纳米复合材料nHA-PA66对感染根管优势菌的体外抑菌效果。方法 采用琼脂扩散法研究
nHA-PA66对牙龈卟啉单胞菌、具核梭杆菌和中间普氏菌的抑菌效果,以所形成的抑菌环直径为评价指标。结果
nHA-PA66粉剂对牙龈卟啉单胞菌和中间普氏菌有较好的抑菌效果,聚合后膜片抑菌效果较粉剂差,两者对具核梭
杆菌无抑菌作用。结论 nHA-PA66对感染根管细菌的抑菌效果不够理想,用作根充材料还需辅以抗菌性能好的
其他物质。
英文摘要
Objective To evaluate the antibacterial activity of nHA-PA66 on the predominant bacteria of infected root canalin vitro.Methods Agar diffusion method was the testing method.Porphyromonas gingivalis(P.gingivalis),Fusobacteria nuclea- tum(F.nucleatum) andPrevotalla intermedius(P.intermedius) were the tested bacteria. The powder and polymerized film of nHA-PA66 were the testmateialswhile the CCQ and filter paper as the control.Results nHA-PA66′s powder showed good ante- bacterial effect on theP.gingivalisandP.intermedius, its filmwasweaker. Both of them had no effect onF.nucleatum.Con- clusion nHA-PA66′s antibacterial effect was not ideal, for better clinical results, some additives can be included.
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