广西地区64例人免疫缺陷病毒感染及艾滋病感染患者口腔病损的临床观察
Investigation on Oral Lesions in 64 Chinese HIV/AIDS Patients in Guangxi Province
作者：陶人川,邓华颉,牙祖科,郭素贞,梁树雄,刘伟
Author：TAO Ren-chuan1,DENGHua-jie1, YAZu-ke1,GUO Su-zhen2,LIANG Shu-xiong2,LIUWei2
收稿日期：2005-08-25 年卷（期）页码：2005,23(04):338-
期刊名称：华西口腔医学杂志
Journal Name：West China Journal of Stomatology
关键字：艾滋病,口腔表征,念珠菌病,
Key words：human immunodeficiency virus,oral lesion,candidiasis,
基金项目：
国家自然科学基金资助项目(30160087);广西青年科学基金资助项目(桂科青0144029)
中文摘要
目的 了解广西人免疫缺陷病毒感染及艾滋病感染(HIV/AIDS)患者口腔病损状况,为我国HIV/AIDS人群口腔疾病的防治提供依据。方法 以经广西区疾病控制中心确诊为HIV/AIDS患者64例为调查对象,由专业人员采集病史,进行口腔专科检查,并将详细记录的结果与世界卫生组织艾滋病感染口腔表征协作中心制定的艾滋病口腔表征分类及诊断标准相比较。结果 64名HIV/AIDS患者,年龄范围为5月~64岁,平均年龄36·1岁,其中男53人,女11人。48名有口腔主诉,以口干、疼痛、吞咽困难为主;口腔表现为口腔念珠菌病39例、口干症20例、口腔溃疡11例、艾滋病相关的牙周病7例、单纯疱疹病毒感染口炎6例、带状疱疹3例、口腔毛状白斑2例、卡波济肉瘤和淋巴节炎各1例。结论 口腔念珠菌病是HIV/AIDS患者最常见的口腔表征,多数患者伴有口干、唾液分泌减少。口腔溃疡患病率与正常群体相比没有提高,但是溃疡严重程度增加。提示HIV/AIDS患者常伴有口腔表征, 并且部分口腔表征出现较早。
英文摘要
Objective To investigate the prevalence, age and gender distribution and clinical features of HIV/AIDS oral le- sions in patients in Guangxi province, and to provide the epidemiological information for prevention and treatment of these diseases in the certain population.Methods Atotal of 64 HIV/AIDS patients were included in this study. All patientsHIV serum-status was confirmed in Guangxi Center of Disease Control (GXCDC). Oral examination was carried out by standardized specialists. HIV/AIDS orofacial lesionswere recorded and diagnosed usingthe EC ClearingHouse Criteria on Oral Problems related toHIVIn- fection (1992).Results Among the total of 64 HIV/AIDS patients included in this study, there were 53 males and 11 females, withmean age of 36·1 years. Candidiasiswasthe most common lesionwiththe pseudomembranoustype predominating.High prevalences of xerostomia, 11 oral ulceration and 7 HIV related periodontitis were noted. 6 Herpetic stomatitis and 3 herpes zoster, 2 oral hairy leukoplakia and 1 Kaposi′s sarcoma and 1 lymphadentitis alsowere found.Conclusion This study shows a high prevalence of candidia- sis, salivary gland disease. Maybe oral ulceration prevalence is not increased, but lesion severity is increased with more severe heperi- form or major RAU. It suggested thatHIV/AIDS usually shows oral lesion and partly can appear in early phase.
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