Objective To discuss the skeletal and dentoalveolar characteristics of asymmetric mandibular excess malocclusions and to discuss the procedures of combined orthodontic-orthonganthic surgery treatments of asymmetric mandibular excess malocclu- sions.Methods 25 cases treated by combined orthodontic-orthognathic surgery treatments were reviewed to find out the special- ties of this kind of therapy.Results The asymmetric of mandible presents anterior and posterior teeth tipped both sagitally and horizontally, as well as upper and lower jaws incompatibility. The pre-surgical orthodontic treatments included decomposition of anterior and posterior teeth, leveling and aligning the teeth etc. The post-surgical orthodontic treatments were to detail the occlu- sions. The patients all got functional and aesthetic good results after the combined orthodontic-orthognathic surgery treatments. Conclusion The asymmetric mandibular excess affects the harmony of the face badly, and the correction of itmust be carried out by the combined orthodontic-orthognathic surgery treatments. The pre-and post-surgical orthodontic treatments are the key stages to make the skeletal corrections stable.