细胞周期素D1在涎腺腺样囊性癌中的表达及意义
Expression and Significance of Cyclin D1 in Human Adenoid Cystic Carcinoma
作者：何巍,何伟,曹选平,李龙江
Author：HE Wei1,HE Wei2,CAO Xuan-ping3,LI Long-jiang1
收稿日期：2005-06-25 年卷（期）页码：2005,23(03):191-
期刊名称：华西口腔医学杂志
Journal Name：West China Journal of Stomatology
关键字：腺样囊性癌,多形性腺瘤,细胞周期素D1,免疫组织化学,
Key words：adenoid cystic carcinoma,pleomorphic adenoma,cyclin D1,immunohistochemistry,
基金项目：
高等学校博士学科点专项科研基金资助项目 (20040610079)
中文摘要
目的 探讨细胞周期素D1(cyclin D1)在涎腺腺样囊性癌中的表达及其与涎腺腺样囊性癌的相关性。方
法 采用免疫组织化学SP法检测cyclin D1蛋白在12例正常涎腺组织(NSG),15例多行性腺瘤(PA)及41例涎腺腺
样囊性癌(ACC)中的表达。结果 cyclin D1在NSG、PA及ACC中的表达率分别为0、53·3%、68·3%,NSG与PA、ACC
组差异均有统计学意义(P
英文摘要
Objective To observe the expression of cyclin D1 in human adnoid cystic carcinoma and its correlation with clini- cal characters.Methods The expression of cycline D1 was evaluated with immunohistochemical method in forty-one cases of human adnoid cystic carcinoma, 15 cases of PA and 12 cases of normal salivary gland tissue.Results The expression of cyclin D1 in normal tissue was negative, significantly different from PA and ACC (P
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