Objective To detect and type human papilloma virus (HPV) in the warts of oral mucosa from HIV-positive patients, and better understand the biological characters of these oral warts. Methods Polymerase chain reaction MR)~used to detect and type HPV infection by concensus HPV primers Gp5+/Gp6+ and specific HPV primers ( HPV6/II，16, 18, 31， 33) in 34 cases of oral mucosa warts from HIV-positive patients. Results The HPV infection rate was 88.2% by consensus HPV primers Gp5十/Gp6十;the HPV infection rate of HPV6/II，16, 18, 31 was respectively 47.06%，11.67 %;2.94%，and 5.88% by specific HPV primers. Conclusion Most lesions of oral warts from HIV-positive patients are associated with the infection of HPV. The low risk HPV6/11 infection is more common than the high risk HPV16, 18, 31.
