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论文摘要

原发性鳃裂癌的临床特点及预后

Clinical Study of Primary Branchiogenic Carcinoma

作者:文光和,黄晓斌,陈钢

Author:WENGuang-he,HUANGXiao-bin,CHENGang

收稿日期:2004-04-25          年卷(期)页码:2004,22(02):120-

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:原发性鳃裂癌,淋巴结,转移,

Key words:primary branchial carcinoma,lymph node,metastasis,

基金项目:

中文摘要

目的 探讨原发性鳃裂癌临床特点及预后。方法 对5例原发性鳃裂癌的临床特点、诊断、鉴别诊断、治疗及预后进行回顾性分析。结果 5例原发性鳃裂癌行肿物扩大切除及根治性颈淋巴结清扫术,术后放射治疗。其中3例有区域性淋巴结转移:1例取出15个淋巴结者有13个有转移,1例取出8个淋巴结者有4个转移。2例在术后8个月和1年内因肿瘤局部复发及远处(肺)转移死亡,1例在术后2年内死亡。2例随访5年,健在。结论 术前与鳃裂囊肿的临床特点极为相似。对颈上部无痛性肿物且有区域性淋巴结肿大者应考虑本病。常规术中快速冰冻切片确诊。肿物扩大切除加根治性颈部淋巴结清扫术可提高治愈率及生存率。

英文摘要

Objective To analyze the clinical feature and prognosis of primary branchial carcinoma.Methods The main method of this studywas reviewing the clinical feature, diagnosis, treatment methods and prognosis of 5 patients suffered from pri- mary branchial carcinoma.Results All of the tumors were excised extensively. All of the patients received radical neck dissec- tion and post-operative radiotherapy. 3 patients had pathologic evident of metastasis in lymph nodes of cervical region. 2 patients died of local recurrence of tumor and metastasis to lung. 1 patient died after post-operative 2 years. 2 patientswere still alive after 5 years′follow-up.Conclusion Primary branchial carcinoma has the very similar clinical featurewith branchial cyst. The diag- nosis should be considered if painless mass and swollen lymph nodes were found in upper neck region of patients. Rapid frozen pathologic section should be made regularly to make the diagnosis clear. The treatment should include extensive excision of tumor and radical neck dissection to improve the cure rate and survival rate.

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