口腔颌面部肿瘤患者T淋巴细胞核仁组成区嗜银蛋白的表达
Expression of Nucleolar Organizer Regions Associated Proteins of T Lymphocytes in the Patients with Oral and Maxillofa- cial Tumors
作者:刘流,温玉明,李龙江,王昌美
Author:LIULiu,WEN Yu-ming,LI Long-jiang,WANG Chang-mei
收稿日期:2004-02-25 年卷(期)页码:2004,22(01):38-
期刊名称:华西口腔医学杂志
Journal Name:West China Journal of Stomatology
关键字:核仁组成区嗜银蛋白,T淋巴细胞,口腔颌面部肿瘤,
Key words:nucleolar organizer regions(NORs),T lymphocyte,oral and maxillofacial tumor,
基金项目:
中文摘要
目的 探讨口腔颌面部肿瘤患者外周血T淋巴细胞核仁组成区嗜银蛋白(Ag-NORs)的表达特点及其在口腔颌面部肿瘤诊断中的价值。方法 采用KL型肿瘤免疫图像分析系统及配套试剂,对86例正常人、102例口腔颌面部良性肿瘤和87例恶性肿瘤患者的外周血T淋巴细胞Ag-NORs进行检测,计算银染核仁面积与细胞核面积的比值(I.S%),然后进行综合分析。结果 口腔颌面部良性肿瘤组患者Ag-NORs表达与正常人组相比明显降低,良性肿瘤组平均I.S%值为(5·72±0·14),正常人组平均I.S%值为(7·87±0·12),两组间有显著性差异(P
英文摘要
Objective To studythe Ag-NORs expressive character ofTlymphocyte in patientswith oral and maxillofacial tumor and evaluate its diagnostic value for the patients.Methods Nucleolar organizer regions(NORs) of T lymphocyte from 86 normal adults, 102 patientswith oral and maxillofacial benign tumors and 87 patientswith oral and maxillofacial malignanttumorswere an- alyzed through KL imaging system.Results There was significant difference among normal adults, benign and malignant patients (P
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