Objective This research estimated shear bond durability of zirconia and different substrates cemented by two self-adhesive resin cements (Clearfil SA Luting and RelyX U100) before and after aging conditioning. Methods Machined zirconia ceramic discs were cemented with four kinds of core material (cobalt-chromium alloy, flowable composite resin core material, packable composite resin, and dentin) with two self-adhesive resin cements (Clearfil SA Luting and RelyX U100). All specimens were divided into eight test groups, and each test group was divided into two subgroups. Each subgroup was subjected to shear test before and after 10 000 thermal cycles. Results All factors (core materials, cements, and thermal cycle) significantly influenced bond durability of zirconia ceramic (P<0 .00 1). after 10 000 thermal cycles, significant decrease was not observed in shear bond strength of cobalt-chromium alloy luted with clearfil sa luting (P>0.05); observed shear bond strength was significantly higher than those of other substrates (P<0 .05). significantly higher shear bond strength was noted in clearfil sa luting luted with cobalt-chromium alloy, flowable composite resin core material, and packable composite resin than that of relyx u100 (P<0 .05). however, significant difference was not observed in shear bond strength of dentin luted with clearfil sa luting and relyx u100 (P>0.05). Conclusion Different core materials and self-adhesive resin cements can significantly affect bond durability of zirconia ceramic.
