炎性衰老在牙周炎中的作用
Effect of inflammaging on periodontitis
作者：王琪, 周欣奕, 丁一
Author：Qi Wang, Xinyi Zhou, Yi Ding
收稿日期：2017-04-16 年卷（期）页码：2018,36(1):99-99-103
期刊名称：华西口腔医学杂志
Journal Name：West China Journal of Stomatology
关键字：牙周炎,炎性衰老,炎性小体,衰老相关疾病,
Key words：periodontitis,inflammaging,inflammasome,age-related diseases,
基金项目：[基金项目] 国家自然科学基金（81200794,81371149）;国家临床重点专科建设项目（牙周病科,2010）;四川省国际科技合作与交流研发项目（2017HH0078）
中文摘要
炎性衰老是机体在衰老的过程中出现慢性、系统性、可控的促炎性反应状态,这种低度慢性炎症与许多衰老相关疾病联系紧密。近年来,炎性衰老在炎症中的作用机制成为治疗和预防炎症性疾病的新方向。本文就炎性衰老及其在牙周炎中的作用进行综述,为研究牙周炎发生发展的机制和治疗方法提供新的思路。
英文摘要
Inflammaging is the chronic, systematic, and controllable upregulation of a pro-inflammation state with advan-cing age. Chronic low-grade inflammation accompanied by sustained stimuli is correlated with various age-related diseases (ARDs). Recent studies on ARDs have prompted further research interest in the inner mechanisms underlying inflammaging to establish prevention and treatment plans for inflammatory diseases. In this article, we discuss inflammaging and its signi-ficant role in periodontitis.
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