槟榔与细胞内活性氧及自噬的关系
Relationship among areca nut, intracellular reactive oxygen species, and autophagy
作者：许智,吕逢源,姜二辉,赵小平,尚政军
Author：Xu Zhi,Lü Fengyuan,Jiang Erhui,Zhao Xiaoping,Shang Zhengjun
收稿日期：2018-10-15 年卷（期）页码：2020,38(1):80-80-85
期刊名称：华西口腔医学杂志
Journal Name：West China Journal of Stomatology
关键字：槟榔,活性氧,自噬,口腔黏膜下纤维性变,口腔癌,
Key words：areca nut,reactive oxygen species,autophagy,oral submucous fibrosis,oral cavity cancer,
基金项目：国家自然科学基金(81901016)
中文摘要
槟榔作为一级致癌物,其与口腔癌的关系受到广泛关注。活性氧（ROS）及自噬水平与肿瘤的发生发展密切相关,研究发现槟榔可诱发细胞内ROS及自噬水平变化。本文结合相关研究进展,对槟榔、细胞内ROS以及自噬之间的关系进行综述。
英文摘要
The relationship between areca nut as a primary carcinogen and oral cancer has been widely concerned. Areca can change the levels of reactive oxygen species (ROS) and autophagy in cells, and the levels of ROS and autophagy are closely related to the occurrence and development of tumors. This paper reviewed the relationships among areca nut, intracellular ROS, and autophagy.
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