促红细胞生成素肝细胞激酶受体及其膜结合配体相关因子在口腔疾病中的表达及作用机制的研究进展
Research progress on the expression and function of erythropoietin-producing hepatomocellular receptors and their receptor-interacting proteins in oral-related diseases
作者:王琦, 刘琰, 赵云, 孙立众, 王琳璇, 韩梅, 米方林
Author:Wang Qi, Liu Yan, Zhao Yun, Sun Lizhong, Wang Linxuan, Han Mei, Mi Fanglin
收稿日期:2019-04-05 年卷(期)页码:2020,38(2):218-218-223
期刊名称:华西口腔医学杂志
Journal Name:West China Journal of Stomatology
关键字:促红细胞生成素肝细胞激酶受体及其膜结合配体,牙周炎,正畸,肿瘤,
Key words:erythropoietin-producing hepatomocellular receptors and their receptor-interacting proteins,periodontitis,orthodontics,tumor,
基金项目:四川省教育厅科研项目(15ZA0210);南充市研发资金项目(16YFZJ0123)
中文摘要
促红细胞生成素肝细胞激酶受体及其膜结合配体(Eph/ephrin)可以通过细胞与细胞间短距离的信号传导,参与调节生长发育,促进疾病发生发展的各个过程。研究Eph/ephrin与口腔相关疾病的机制可以为口腔疾病的治疗提供新的思路。近年来,针对Eph/ephrin通路调控口腔相关疾病,尤其是在牙周疾病防治、正畸骨改建以及口腔肿瘤的生物学治疗领域的研究逐渐深入,本文即对这3个方面的研究进展进行综述。
英文摘要
Erythropoietin-producing hepatomocellular receptors and their receptor-interacting proteins (Eph/ephrin) can participate in the regulation of growth and development and promote the development of diseases through short-distance signal transduction between cells. To study the mechanism of Eph/ephrin and oral-related diseases, we provided a new theoretical basis and a strategy for the treatment of oral diseases. The Eph/ephrin pathway has been used to regulate oral diseases, especially in periodontal disease prevention, orthodontic bone reconstruction, and biological treatment of oral tumors. This paper reviews the research progress of Eph/ephrin pathway in oral-related diseases.
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