CO2点阵激光早期控制唇裂二期整复术后瘢痕的疗效观察
Effect of CO2 fractional laser on the early control of scar post-secondary repair in patients with a cleft lip
作者：李媛媛, 吴敏, 刘明曦, 解晨阳, 郑谦, 石冰, 李承浩
Author：Li Yuanyuan, Wu Min, Liu Mingxi, Xie Chenyang, Zheng Qian, Shi Bing, Li Chenghao
收稿日期：2019-11-18 年卷（期）页码：2020,38(6):657-657-661
期刊名称：华西口腔医学杂志
Journal Name：West China Journal of Stomatology
关键字：CO<sub>2</sub>点阵激光,唇裂术后二期整复术,瘢痕,
Key words：CO2 fractional laser,secondary repair of the cleft lip,scars,
基金项目：四川大学华西口腔医院临床研究项目(LCYJ2019-10)
中文摘要
目的 观察比较CO2点阵激光早期控制唇裂术后二期整复术术区瘢痕的临床疗效。方法 治疗组为43例接受唇裂术后鼻唇畸形二期整复术的患者,早期采用CO2点阵激光治疗,对照组为70例曾接受一期唇裂手术的患者,对两组6个月后的瘢痕恢复情况进行比较;分析术后距离激光开始治疗时间的长短,性别两因素对激光治疗瘢痕疗效的差异。结果 1）治疗组的疗效优于对照组（P<0.000 1）,治疗组中显效和有效所组成的总有效率达90.7%;2）男女疗效差异无统计学意义（P=0.487）,手术后1年内的患者,手术后距离开始瘢痕治疗的时间<3个月与≥3个月之间,疗效无明显统计学差异（P=0.055）。结论 CO2点阵激光在唇裂二期整复术术后瘢痕的治疗中具有较为确切的疗效。且与患者的性别无明显相关性。手术后1年内的患者,术后距离开始瘢痕治疗的时间<3个月和≥3个月疗效无差异,因此在唇裂二期手术后的1年内早期对瘢痕进行干预可获得良好的效果。
英文摘要
ObjectiveTo observe and compare the clinical efficacy of CO2fractional laser in the early control of scar post-secondary repair in patients with a cleft lip.MethodsIn the treatment group, 43 patients with secondary repair of cleft lip were treated via CO2fractional laser. The control group covered 70 patients post-cheiloplasty. The effect in the two groups after six months was compared. The duration from the beginning of the laser treatment to surgery and patient gender were analyzed to determine if they affected the efficacy of the laser treatment for scars.Results1) The curative effect in the treatment group was better than that in the control group (P<0 .000 1), the total effectiveness rate was 90.7% in the treatment group. 2) no significant statistical difference in efficacy was observed between men and women (P=0.487). Moreover, no significant statistical difference in efficacy (P=0.055) was observed among patients one year after surgery, within the duration of <3 months, and within the duration of ≥3 months.ConclusionCO2fractional laser had a definite effect on the treatment of scar post-secondary repair in patients with a cleft lip. No significant correlation was observed between treatment effect and patient gender, and no difference was noted among patients one year after surgery. In the beginning of the laser treatment, no difference was observed between the durations of <3 months and ≥3 months after the reconstruction, therefore, early intervention of scars a year after secondary repair of a cleft lip can achieve good results.
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