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论文摘要

含精氨酸的抗敏抛光膏对暴露牙本质表面变异链球菌黏附的影响

Effect of an arginine-containing polishing paste on Streptococcus mutans adhesion to exposed dentin surfaces

作者:刘音辰 付东杰 黄翠 裴丹丹 孙华岭

Author:Liu Yinchen, Fu Dongjie, Huang Cui, Pei Dandan, Sun Hualing.

收稿日期:2013-01-11          年卷(期)页码:2013,31(5):453-453-456

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:精氨酸,抛光膏,黏附,

Key words:arginine,polishing paste,adhesion,

基金项目:

国家自然科学基金资助项目(81070852,81171010)

中文摘要

目的 研究含精氨酸抗敏抛光膏对暴露牙本质表面变异链球菌黏附的影响。方法 暴露牙本质小管,使用浮石粉和抗敏抛光膏处理表面,观察其粗糙度的变化。体外培养变异链球菌,观察其在牙本质片表面黏附及葡糖基转移酶(GTFs)基因表达情况。结果 使用浮石粉及抗敏抛光膏均能有效降低表面粗糙度,抗敏抛光膏处理后的牙本质能明显抑制gtfB和gtfC基因的表达。结论 含精氨酸抗敏抛光膏能抑制变异链球菌黏附及gtfB和gtfC基因的表达,对敏感牙本质区域龋病发生具有一定防治作用。

英文摘要

Objective To evaluate the effect of an arginine-containing antihypersensitivity polishing paste on Streptococ-cus mutans (S. mutans) adhesion to treated dentin.Methods Dentin discs were treated with acid to expose dentin tubules, and then polished with either pumice or a polishing paste containing arginine. The surface roughness of the treated dentin was measured. The effects of dentin treatment on S. mutans adhesion and glucosyltransferase (GTFs) gene expression were also evaluated.Results The surface roughness decreased after polishing with both pumice and arginine-containing polishing paste. Moreover, the polishing paste affected gtfB and gtfC expressions.Conclusion The arginine-containing polishing paste affects S. mutans adhesion, as well as gtfB and gtfC expressions. The polishing paste may be used to prevent caries in exposed dentin areas.

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