Objective To evaluate the post-operative pain level and two years healing of one-visit endodontic treatment for infected root canals. Methods 76 infected cases were included in one-visit root canal therapy group and 62 infected cases in two-visit group using calcium hydroxide as an interappointment medicament. A comparison of the clinical results was done between the two groups. The main assessments included pre- and post-operative pain evaluated by patients and dentists, and the healing response after six months, one year and two years. Results There was no statistical significance between the groups regarding pain 7 days after operation and two years′ cure rate. After six months, one year and two years, the cure rates of one-visit group were 68.4%, 92.1%, 98.7%, while those of two-visit group were 64.5%, 91.9%, 96.8%, respectively. Conclusion One-visit endodontic treatment for infected root canals has the same clinical efficacy as two-visit in regarding to post-operative pain level and shortterm healing.
