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论文摘要

异丙酚、瑞芬太尼和七氟烷、瑞芬太尼用于小儿唇腭裂手术麻醉的临床观察

Clinical comparison of propofol and remifentanil anaesthesia with sevoflurane and remifentanil anaesthesia for children with cleft lip and palate repair surgery

作者:邓晓倩 王淼 吉阳

Author:DENG Xiao-qian, WANG Miao, JI Yang

收稿日期:2009-10-25          年卷(期)页码:2009,27(05):531-531-534

期刊名称:华西口腔医学杂志

Journal Name:West China Journal of Stomatology

关键字:异丙酚,瑞芬太尼,七氟烷,唇腭裂修复术,

Key words:propofol,remifentanil,sevoflurane,cleft lip and palate repair surgery,

基金项目:

中文摘要

目的比较异丙酚、瑞芬太尼和七氟烷、瑞芬太尼用于小儿唇腭裂手术麻醉的效果和安全性。方法选择40例择期行唇腭裂修复术的患儿为研究对象,随机分为2组。PR组20例,采用异丙酚和瑞芬太尼麻醉;S组20例,采用七氟烷和瑞芬太尼麻醉。记录2组患儿在麻醉诱导前,麻醉诱导后15、30 min,拔管后1 min的心率(HR)、平均动脉压(MAP)、脉搏血氧饱和度(SPO2);并记录拔管时间、术后躁动分级,以及恶心呕吐和气道并发症的发生情况。结果2组患儿的性别、年龄、体重、手术种类和手术时间的差异均无统计学意义(P>0.05)。PR组在麻醉诱导后有2例患儿因心率较慢而使用阿托品,分别为3岁和8岁,前者心率低于100次/min,后者低于70次/min。与诱导前相比,PR组在拔管后1 min 心率明显加快,S 组在诱导后30 min 和拔管后1 min 心率明显加快(P0.05)。2组的术后拔管时间没有统计学差异(P>0.05)。PR组发生术后躁动者有2例,S组有8例,其差异有统计学意义(P

英文摘要

Objective To compare the clinical effects and safety of propofol and remifentanil anaesthesia with

sevoflurane and remifentanil anaesthesia for cleft lip and palate repair surgery in children. Methods Forty children

undergoing elective cleft lip and palate repair surgery were randomly divided into two groups, 20 in each group.

Group PR: Propofol and remifentanil anaesthesia; and group S: Sevoflurane and remifentanil anaesthesia. Heart rate

(HR), mean arterial pressure(MAP), pulse oxygen saturation(SPO2), and end tidal carbon dioxide(ETCO2) were observed,

and recorded at the time before the induction(T0), after 15 min of induction(T1), after 30 min of in-duction (T2), and after 1 min of extubation(T3). The time to extubation, incidence of restlessness, postoperative nausea and vomiting, and the complication of the airway were recorded. Results There were no significantly differences between the two groups with respect to sex, age, weight, category of operation, and the time of operation. In group PR, after the period of induction, two children used atropine for bradycardia. One was 3 years old, and the other was 8 years old. The HR of former was lower than 100 beats per minute, and the latter was lower than 70 beats per minute. The average of HR in group PR was increased after 1 min of extubation compared with that before induction(P

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