Objective To compare the regional load deflection rate（LDR） of multiloop edgewise arch wire （MEAW） of three dimensions with coupled use of two dimension brackets in the individual interbracket span, to understand the mechanical properties of MEAW. Methods The MEAW arch wires of stainless steel of three dimensions, 0.41 mm×0.56 mm, 0.43 mm×0.64 mm and 0.46 mm×0.64 mm, were bent into single L-loop. The study was performed with the coupled use of 0.41 mm×0.56 mm wires with 0.46 mm×0.64 mm bracket（A bracket） and 0.43 mm× 0.64 mm, 0.46 mm×0.64 mm wires with 0.56 mm×0.71 mm bracket（B bracket）. The LDR of each L -loop at the individual interbracket span when loading and unloading was measured. The data were analysed by SPSS 11.0. Results Compared the regional LDR for the couple of 0.41 mm×0.56 mm L-loop with A bracket with those for the couple of 0.43 mm×0.64 mm L-loop with B bracket, the former showed lower value than the latter at regions between the upper central and lateral incisor, the lower central and lateral incisor, and between the lower lateral incisor and canine（P
